Long-Term Release The new controlled-release formulation of Ambien CR (zolpidem tartrate extended-release tablets) provides a novel approach to sleep assistance. Buy ambien online without prescription dual-layer technology is used in this drug to successfully treat problems related to both the onset and maintenance of sleep. A single tablet given right before bed is the usual dosage advice for Ambien CR. Compared to immediate-release variants, the extended-release formulation permits a lower starting dose, which may lessen the likelihood of sleepiness the following day.